|
KMID : 0377520140390010001
|
|
Chung-Ang Journal of Medicine
2014 Volume.39 No. 1 p.1 ~ p.4
|
|
|
A Case of AMA (Anti-mitochondrial Antibody) Negative Primary Biliary Cirrhosis
|
|
Kim Kwang-Seok
Lee Jung-Hyun
Hur Jae-Young
Byun Se-Jin
Park Ki-Hyun
Kim Byung-Kook
Park A-Young
|
|
|
Abstract
|
|
|
|
Primary biliary cirrhosis (PBC) is a chronic cholestatic disease with progressive course. It has a highly disease-specific autoantibody, the anti-mitochondrial antibody (AMA) which was found in 90-95% of patients. Therefore the diagnosis of AMA negative PBC could be delayed and a chance of treatment would be missed. This case is the AMA negative primary biliary cirrhosis which was confirmed by liver biopsy. A 58-year-old female patient was diagnosed as the fatty liver disease without liver biopsy 2 years ago when she was referred for the evaluation of abnormal liver function test. At that time, serologic test of autoimmune hepatitis including AMA was all negative. Two year later, PBC was confirmed by liver biopsy. After prescription of ursodeoxycholic acid, she has been improved in clinical course and liver function test.
|
|
|
KEYWORD
|
|
|
Primary biliary cirrhosis, Anti-mitochondrial antibody, Cholestatic
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|